Antipyretic potential of methanol extract of bark of Strychnos colubrina L. was investigated. The dried bar of Strychnos colubrina L. was extracted with methanol. The antipyretic effects of extracts of bark of Strychnos colubrina L. were investigated at doses 100 and 250 mg/kg b.w. using yeast induced pyrexia in rats. Strychnos colubrina L. extracts produced significant (P<0.05) dose-dependent reduction in hyperpyrexia in rats throughout the observation period of 5 hrs. The results of present study suggest that extracts of Strychnos colubrina L. possess potent antipyretic effects and could serve as a base for future drugs.
Loading....